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Panacur® Equine Guard 10% w/v Oral Suspension PML

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Original price £27.95 - Original price £27.95
Original price
£27.95 - £27.95
Current price £27.95
SKU 50050

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Prescription Medicines

Upon purchasing this product you will receive a phone call or email from our team to check that you have ordered the correct product (and correct amounts) for your animal's needs.

PLEASE NOTE- You will be required to complete a short questionnaire before we are able to despatch your products. This may mean that the delivery date is prolonged and is subject to when we have received the required information.

Use the risk assessment by CANTER or give us a call to discuss your horses worming requirements.
Panacur Equine Guard liquid horse wormer is a five day course that treats encysted redworm in horses. One bottle of Panacur Guard will treat 600kg body weight of horse. These horse wormers are suitable for use in pregnant mares and young foals.
Data Sheet

Panacur® Equine Guard 10% w/v Oral Suspension

Species:Horses and other equidae
Therapeutic indication:Pharmaceuticals: Endoparasiticides: Anthelmintics for horses
Active ingredient:Fenbendazole
Product:Panacur® Equine Guard 10% w/v Oral Suspension
Product index:Panacur® Equine Guard
Withdrawal notes:Not to be used in horses intended for human consumption.
Qualitative and quantitative composition
Active substance(s): % w/v
Fenbendazole 10.000
Sodium Methyl Parahydroxybenzoate 0.200
Sodium Propyl Parahydroxybenzoate 0.0216
Benzyl Alcohol 0.4835
For the full list of excipients, see section “Pharmaceutical particulars”.
Pharmaceutical form
Oral suspension.
A white, aqueous suspension.
Clinical particulars
Target Species
Horses and other equines.
Indications for use
For the treatment and control of adult and immature roundworms of the gastro-intestinal tract in horses and other equines.
The product is also effective for the treatment and control of encysted mucosal 3rd and 4th stage small strongyle larvae and is also effective against encysted inhibited 3rd stage small strogyle larvae in the mucosa.
The product is also effective in controlling other immature and mature roundworms including large redworm (Strongylus edentatus and Strongylus vulgaris) and migrating large redworm, Ascarids (Parascaris equorum), Oxyuris and Strongyloides species and benzimidazole susceptible adult and immature small strongyles (Cyathostomes).
The product also has an ovicidal effect on nematode eggs.
None known.
Special warnings for each target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
∙ Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
∙ Under dosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to fenbendazole has been reported in cyathostomes in horses. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Special precautions for use
Assess bodyweight as accurately as possible before calculating the dosage.
Intensive use or misuse of anthelmintics can give rise to resistance. To reduce this risk, dosing programmes should be discussed with your veterinary surgeon.
Operator warnings
Direct contact with the skin should be kept to a minimum. Wear suitable protective clothing including impermeable rubber gloves.
Wash hands after use.
Adverse Reactions
None known.
Use during pregnancy or lactation
Pregnant mares and young foals may also be safely treated with fenbendazole at therapeutic dosage levels.
None known.
Amounts to be administered and administration route
For oral administration.
No dietary control is required before or after treatment.
For the treatment and control of migrating and tissue larval stages of large strongyles, encysted mucosal 3rd and 4th stage small strongyle larvae and encysted inhibited 3rd stage small strongyle larvae in the mucosa administer 5 ml of the product per 65 kg bodyweight daily for 5 days (= 7.5 mg fenbendazole/kg bodyweight daily for 5 days).
The product can be easily administered by mixing with grain or concentrate feed. The full daily dosage must be given as one administration.
To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.
Recommended dosing programme
Treatment of encysted inhibited and encysted mucosal dwelling larvae should be performed in the autumn (ideally late October/November) and again in the Spring (ideally in February). However, for horses that fail to maintain condition or bought-in horses with unknown worming history, the treatment can be given at any time of the year.
Shake container before use.
Treatment with this product should form part of an integrated worming plan. Consult with your supplier for advice regarding wormers to use throughout the year.
Benzimidazoles have a wide margin of safety.
Withdrawal periods
Not to be used in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.
Pharmacological particulars
ATC Vet Code: QP52 AC13
Pharmacodynamic properties
Fenbendazole is an anthelmintic belonging to the benzimidazole-carbamate group. It acts by interfering with the energy metabolism of the nematode.
The anthelmintic affects both adult and immature stages of gastro-intestinal and respiratory nematodes. This anthelmintic efficacy is based on inhibition of the polymerisation of tubulin to microtubuli.
Pharmacokinetic properties
Fenbendazole is only partly absorbed from the intestine and reaches maximum plasma concentration 6 (4-8) hours after oral administration.
Fenbendazole is metabolised mainly by enzymes of the cytochrome P -450 system in the liver. The major oxidative metabolite is fenbendazole sulfoxide which is further metabolised to fenbendazole sulfone.
Fenbendazole and its metabolites are distributed throughout the body but highest concentrations are found in the liver.
Fenbendazole and its metabolites are detectable in the plasma only during the first 48 hours following drug administration at a single dose rate of 10 mg fenbendazole/ kg bodyweight.
Administration of fenbendazole at a dose rate of 10 mg/kg bodyweight daily for five consecutive days lead to accumulation of fenbendazole during the multiple dosing period whereas the concentrations of its two metabolites show only a slight increase. After the last administration on day 5, all three compounds are eliminated from blood very rapidly, within two or three days.
The elimination of fenbendazole and its metabolites occurs primarily via the faeces.
Pharmaceutical particulars
Sodium Methyl Parahydroxybenzoate
Sodium Propyl Parahydroxybenzoate
Benzyl alcohol
Silica colloidal anhydrous
Carmellose sodium
Povidone K25
Sodium Citrate Dihydrate
Citric Acid Monohydrate
Water Purified
Major incompatibilities
None known.
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Special precautions for storage
Do not freeze.
Immediate packaging
A 225 ml, multidose opaque, white, high density polyethylene bottle. The closure is tamper proof with an aluminium foil seal and a polypropylene cap (screw-fit).
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements. Dangerous to fish and aquatic life. Do not contaminate ponds, waterways or ditches with the product or used container.
Marketing Authorisation Holder (if different from distributor)
Marketing Authorisation Number
UK: Vm 01708/4466

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